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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
15-05-2017 – 19-05-2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
Experimental test result performed using standard test guidelines
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
no
Type of method:
flask method
Key result
Water solubility:
754.801 mg/L
Conc. based on:
test mat.
Temp.:
30 °C
Remarks on result:
other: other details not specified
Details on results:
The water solubility for the test item 4-methyl-1-phenyl-3-pyrazolidone was found to be 754.801 mg/L at 30°C.

Table 2:

Sample stirring

 

Concentration obtained on

the basis of standard curve

Dilution factor

Solubility value obtained (mg/L)

24 hour

 

 

 

48 hour

41.9352

20

838.704 mg/L

72 hour

33.5449

20

670.898 mg/L

Considering the water solubility for 48 hrs and 72 hrs the mean water solubility was calculated as follows:

Mean water solubility value for 48 hour run sample + 72 hour run sample

= (838.704+670.898)/2

= 754.801 mg/L

Conclusions:
The water solubility determination of test chemical was done by spectrophotometric method and it was determined to be 754.801 mg/L at 30°C.
Executive summary:

The water solubility determination of test chemical was done as per the OECD guideline 105 byspectrophotometric analytical method as per OECD 101. The solubility of test chemical in water was determined to be 754.801 mg/L at 30°C. Thus the chemical is considered to be moderately soluble in water.

Description of key information

The water solubility determination of test chemical was done as per the OECD guideline 105 byspectrophotometric analytical method as per OECD 101. The solubility of test chemical in water was determined to be 754.801 mg/L at 30°C. Thus the chemical is considered to be moderately soluble in water.

Key value for chemical safety assessment

Water solubility:
754.801 mg/L
at the temperature of:
30 °C

Additional information

The water solubility determination of test chemical was done as per the OECD guideline 105 byspectrophotometric analytical method as per OECD 101. The solubility of test chemical in water was determined to be 754.801 mg/L at 30°C. Thus the chemical is considered to be moderately soluble in water.