Registration Dossier
Registration Dossier
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EC number: 617-648-0 | CAS number: 849727-62-4
Density
Administrative data
- Endpoint:
- relative density
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 23 September - 29 December 2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 016
- Report date:
- 2016
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 109 (Density of Liquids and Solids)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.3 (Relative Density)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7300 (Density / Relative Density / Bulk Density)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- pycnometer method
Test material
- Reference substance name:
- 3-(2-CHLOROETHYL)-9-HYDROXY-2-METHYL-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE HYDROCHLORIDE (1:1)
- EC Number:
- 617-648-0
- Cas Number:
- 849727-62-4
- Molecular formula:
- C11H11ClN2O2.HCl
- IUPAC Name:
- 3-(2-CHLOROETHYL)-9-HYDROXY-2-METHYL-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE HYDROCHLORIDE (1:1)
- Test material form:
- solid: particulate/powder
Constituent 1
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): T002006
- Substance type: almost white to ochre solid
- Physical state: solid
- Analytical purity: 97.5%
- Lot/batch No.: I15BB0722
- Expiration date of the lot/batch: 2017-02-21
- Storage condition of test material: At room temperature (15-25°C)
Results and discussion
Density
- Key result
- Type:
- relative density
- Density:
- 1.6 g/cm³
- Temp.:
- 20 °C
Any other information on results incl. tables
The density (ρ) of a substance is the quotient of its mass and its volume and is expressed in SI units of kg/m³.
The individual measurements were obtained with an accuracy of <0.02 g/cm³.
The individual density measurements were 1.595 g/cm³ (test 1) and 1.597 g/cm³ (test 2).
Applicant's summary and conclusion
- Conclusions:
- A gas comparison stereopycnometer was used for the determination of the density of JNJ-1692405-AAC (T002006).The density of the test item at 20ºC was 1.60 g/cm³ (1.60 x 10³ kg/m³).
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