Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
pH
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
comparable to guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: OECD 122
Principles of method if other than guideline:
A pH meter is essentially a voltmeter with high input impedance which measures the voltage of an electrode sensitive to the hydrogen ion concentration, relative to another electrode which exhibits a constant voltage
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
N-hydroxyphthalimide
EC Number:
208-358-1
EC Name:
N-hydroxyphthalimide
Cas Number:
524-38-9
Molecular formula:
C8H5NO3
IUPAC Name:
N-hydroxyphthalimide
Details on test material:
SMILES:ON1C(=O)c2ccccc2C1=O
Specific details on test material used for the study:
- Name of test material (as cited in study report): 2-hydroxy-1H-isoindole-1,3(2H)-dione
- Molecular formula: C8 H5 N O3
- Molecular weight: 163.132 g/mol
- Smiles notation: c12c(C(=O)N(C1=O)O)cccc2
- InChI: 1S/C8H5NO3/c10-7-5-3-1-2-4-6(5)8(11)9(7)12/h1-4,12H
- Substance type: Organic
- Physical state: Solid

Results and discussion

pH value
Key result
pH value:
5.31
Temp.:
27 °C
Concentration:
1 other: %w/v
Acidity or alkalinity
Key result
Acidity or alkalinity:
acidity
Value:
5.31

Applicant's summary and conclusion

Conclusions:
The pH of 1% w/v solution of the test item 2-hydroxy-1H-isoindole-1,3(2H)-dione (CAS No524-38-9)was 5.31 at27 °C.
Executive summary:

The pH determination of test item 2-hydroxy-1H-isoindole-1,3(2H)-dione(CAS No 524-38-9) was done following OECD guideline 122. pH of 1% w/v solution was measured with the help of pH meter and it was observed to be 5.31at 27 °C.

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