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EC number: 208-358-1 | CAS number: 524-38-9
Endpoint summary
Administrative data
Description of key information
Appearance:
On the basis of physical observation,the chemical 2-hydroxy-1H-isoindole-1,3(2H)-dione was observed to be white coloured amorphous powder in appearance.
Melting point:
The melting point determination of 2-hydroxy-1H-isoindole-1,3(2H)-dione (CAS No. 524-38-9) was done following OECD Guideline 102 and according to the metal block capillary method. The test was conducted in replicates and mean melting temperature range was determined to be 230.8- 233.6°C at 975.4hPa.
Boiling point:
The boiling point determination of 2-hydroxy-1H-isoindole-1,3(2H)-dione (CAS No. 524-38-9) was done following OECD Guideline 103 and according to the method of Siwoloboff. The test item does not show string of bubbles upto 300 °C inferring to be greater than 300°C at 976.2 hPa.
Density:
The density of test item 2-hydroxy-1H-isoindole-1,3(2H)-dione (CAS No. 524-38-9)was determined following OECD Guideline 109 and according to the Adapted from ASTM D854-02 using glass pyknometer.The mean density of 2-hydroxy-1H-isoindole-1,3(2H)-dione was determined to be 1.616 g/cm³ at 20°C and 977.0 hPa.
Particle Size Distribution:
The particle size distribution of test item N-hydroxyphthalimide (CAS No. 524-38-9 ) was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was determined to be in the range of 150 micron to 25 micron.
Vapor Pressure:
MPBPVP v1.43 was used to estimate the vapor pressure of 2-hydroxyphthalimide. The estimated vapor pressure of 2-hydroxyphthalimide at 25 degC was 6.2E-008Pa.
Data from handbooks and authoritative databases suggest that the estimated vapor pressure of 2-hydroxyphthalimide at 25 degC was 3.27E-008Pa.
Partition Coefficient:
Data from handbooks and authoritative databases suggest that the estimated logPow of N-hydroxyphthalimide was 0.14.
Based on these values,N-hydroxyphthalimide can be considered to be hydrophillic in nature
Water Solubility:
WSKOW v1.42 was used to estimate the water solubility of 2-hydroxyphthalimide. The estimated water solubility of 2-hydroxyphthalimide at 25 deg C was 50450 mg/l.
Data from handbooks and authoritative databases suggests that the estimated water solubility of 2-hydroxyphthalimide at 25 deg C was 50500 mg/l.
These value indicates that 2 -hydroxyphthalimide is highly soluble in water.
Explosiveness:
The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties
Oxidising properties:
The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with oxidising properties and hence, the classification procedure does not need to be applied
Viscosity:
The study does not need to be conducted because the substance is a solid
Additional information
Appearance:
On the basis of physical observation,the chemical 2-hydroxy-1H-isoindole-1,3(2H)-dione was observed to be white coloured amorphous powder in appearance. Other supporting studies from various reliable sources such as authoritative database and handbook also indicates that the chemical 2-hydroxy-1H-isoindole-1,3(2H)-dione was observed to be Yellowish or colorless solid in appearance.
Melting point:
The melting point determination of 2-hydroxy-1H-isoindole-1,3(2H)-dione (CAS No. 524-38-9) was done following OECD Guideline 102 and according to the metal block capillary method. The test was conducted in replicates and mean melting temperature range was determined to be 230.8- 233.6°C at 975.4hPa. Other supporting studies from various reliable sources such as authoritative database and handbook also indicates that the melting point of chemical 2-hydroxy-1H-isoindole-1,3(2H)-dione was determined to be in the range of 223 degree C to 237 degree C. As the data from lab has K1 reliability and the test was performed using OECD guidelines which has the value of melting temperature as 230.8 degree C to 233.6 degree C, thus considered as key study for the chemical safety assessment.
Boiling point:
The boiling point determination of 2-hydroxy-1H-isoindole-1,3(2H)-dione (CAS No. 524-38-9) was done following OECD Guideline 103 and according to the method of Siwoloboff. The test item does not show string of bubbles upto 300 °C inferring to be greater than 300°C at 976.2 hPa.
Density:
The density of test item 2-hydroxy-1H-isoindole-1,3(2H)-dione (CAS No. 524-38-9)was determined following OECD Guideline 109 and according to the Adapted from ASTM D854-02 using glass pyknometer.The mean density of 2-hydroxy-1H-isoindole-1,3(2H)-dione was determined to be 1.616 g/cm³ at 20°C and 977.0 hPa.
Other supporting studies from various reliable sources such as authoritative database and handbook also indicates that the density of chemical 2-hydroxy-1H-isoindole-1,3(2H)-dione was determined to be in the range of 1.58 g/cm3 to 1.601 g/cm3
As the data from lab has K1 reliability and the test was performed using OECD guidelines which has the value of density as 1.616 g/cm3 at 20 degree C, thus considered as key study for the chemical safety assessment.
Particle Size Distribution:
The particle size distribution of test item N-hydroxyphthalimide (CAS No. 524-38-9 ) was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was determined to be in the range of 150 micron to 25 micron.
Vapor Pressure:
MPBPVP v1.43 was used to estimate the vapor pressure of 2-hydroxyphthalimide. The estimated vapor pressure of 2-hydroxyphthalimide at 25 degC was 6.2E-008Pa.
Data from handbooks and authoritative databases suggest that the estimated vapor pressure of 2-hydroxyphthalimide at 25 degC was 3.27E-008Pa.
Partition Coefficient:
Data from handbooks and authoritative databases suggest that the estimated logPow of N-hydroxyphthalimide was 0.14.
Based on these values,N-hydroxyphthalimide can be considered to be hydrophillic in nature
Water Solubility:
WSKOW v1.42 was used to estimate the water solubility of 2-hydroxyphthalimide. The estimated water solubility of 2-hydroxyphthalimide at 25 deg C was 50450 mg/l.
Data from handbooks and authoritative databases suggests that the estimated water solubility of 2-hydroxyphthalimide at 25 deg C was 50500 mg/l.
These value indicates that 2 -hydroxyphthalimide is highly soluble in water.
Explosiveness:
The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties
Oxidising properties:
The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with oxidising properties and hence, the classification procedure does not need to be applied
Viscosity:
The study does not need to be conducted because the substance is a solid
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