Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 619-383-6 | CAS number: 98967-40-9
XRD-498 was evaluated for dermal sensitization potential using a modified Buehler method. Ten male Hartley albino guinea pigs received three applications of XRD-498 during the induction phase of the study. A positive control group recieved three applications of 10% DER 331 epoxy resin during the induction phase. The respective groups were challenged with XRD-498 or 10% DER 331 two weeks after the last induction application. The condition of the test sites was assessed approximately 24 and 48 hours after the challenge application. Challenge application of the positive control caused slight to moderate erythema in seven of ten animals. It was therefore concluded that, under the conditions of this study, XRD-498 did not cause delayed contact hypersensitivity in guinea pigs.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Close Do not show this message again