Registration Dossier
Registration Dossier
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EC number: 201-557-4 | CAS number: 84-74-2
Repeated dose toxicity: dermal
Administrative data
- Endpoint:
- repeated dose toxicity: dermal
- Adequacy of study:
- other information
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 2 013
Materials and methods
Test animals
- Species:
- rabbit
Administration / exposure
- Duration of treatment / exposure:
- 90 days
Doses / concentrations
- Remarks:
- Doses / Concentrations:
0.5, 1.0, 2.0, 4.0 mL/kg bw/d
Basis:
Results and discussion
Target system / organ toxicity
- Critical effects observed:
- not specified
Any other information on results incl. tables
Slight irritation and dermatitis were reported without information on the dose level at which it was observed. Slight renal damage was reported at 4.0 mL/kg bw/d.
Applicant's summary and conclusion
- Conclusions:
- Slight irritation and dermatitis were reported without information on the dose level at which it was observed. Slight renal damage was reported at 4.0 mL/kg bw/d.
- Executive summary:
In this poorly documented study (Lehmann 1955) on rabbit slight skin irritation and dematistis were reported. Also slight renal damage was reported at 4.0 mL/kg bw/d.
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