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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
72 hours
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Justification for type of information:
Performed to company standards, following principles of OECD methodsAdditional work performed to assess solublity at reduced pH
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
Additional pH levels used
GLP compliance:
no
Type of method:
flask method
Specific details on test material used for the study:
Batch number of test material : A-09-3004
Key result
Water solubility:
ca. 0.06 mg/L
Conc. based on:
test mat.
Loading of aqueous phase:
100 mg/L
Incubation duration:
72 h
Temp.:
20 °C
pH:
7
Water solubility:
ca. 6.1 mg/L
Conc. based on:
test mat.
Loading of aqueous phase:
100 mg/L
Incubation duration:
72 h
Temp.:
20 °C
pH:
1.5
Remarks on result:
other: solublity in acid media
Details on results:
Solublity was assessed over a range of pH vlaues, showing higher solublity under acid conditions
Conclusions:
This demonstrates that the solubility in water is very low but it is affected by pH, the substance being more soluble at extreme pH’s. The highest solubility was observed at a pH of 1.5

Description of key information

Solubility in water is very low but it is affected by pH, the substance being more soluble at extreme pH. Solubility was6 mg/l at pH 1.5

Key value for chemical safety assessment

Water solubility:
0.06 mg/L
at the temperature of:
20 °C

Additional information