Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no study available
Additional information:

In accordance with section 2 of REACH (regulation(EC) No 1907/2006) Annex VII, skin sensitisation (required in Annex VII section 8.3) does not need to be conducted as the substance contain between 40 and 60% of free 3-aminomethyl-3,5,5-trimethylcyclohexamine (IPDA) which has corrosive properties. However, 3 -aminomethyl-3,5,5 -trimethycyclohexamine (IPDA) is also known to be a skin sensitizer. Consequently, the UVCB substance it is highly likely that the UVCB substance will exhibit the same skin sensitization potential.


Migrated from Short description of key information:
The UVCB substance contain between 40 and 60% of free 3-aminomethyl-3,5,5-trimethylcyclohexamine (IPDA) which is known to be a skin sensitizer.

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no study available

Justification for classification or non-classification

- skin sensitisation:

Based on the above stated assessment of the skin sensitisation potential regarding the main constituent (3 -aminomethyl-3,5,5 -trimethylcyclohexamine) of the UVCB substance, it needs to be classified as R43 (May cause sensitisation by skin contact) according to Council Directive 2001/59/EC (28th ATP of Directive 67/548/EEC) and Skin Sens. 1 (H317: may cause an allergic skin reaction) according CLP (Regulation (EC) No 1272/2008 Of The European Parliament And Of The Council) as implementation of UN-GHS in the EU.

- respiratory sensitisation:

As no data on respiratory sensitization is available for the UVCB substance a classification is not possible according to Council Directive 2001/59/EC (28th ATP of Directive 67/548/EEC) and accordingCLP (Regulation (EC) No 1272/2008 Of The European Parliament And Of The Council) as implementation of UN-GHS in the EU.