Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

The test substance had a maximum biodegradation of 5% after 28 days of activated sludge contact in two independent ready biodegradability studies. Therefore, the test substance is not readily biodegradable under the conditions of the studies.

The substance was found to be relatively stable at pH 4 in a hydrolysis study performed according to OECD 111 with a half-life time greater than 1 year. Due to low solubility at pH 7 and pH 9 no hydrolysis rate could be determined at the these pH's.

Due to the complexity of the structure and presence of multiple constituents it was also not possible to determine the dissociation constants experimentally.

No conclusion on persistence can be reached based on available information.

The partition coefficient of the UVCB substance could also not be determined experimentally, but modelling from the two main constituents was performed and led to a log Kow of 1.75 for isophoronediamine (58%) and a log Kow of 6.44 was estimated for IPDA-BADGE-IPDA (31%). Taken into consideration that the modelling is related to the neutral molecules that only appear at pH 10 and above, due to the fact that IPDA-BADGE-IPDA is many times protonated at pH 7 (azote groups), the molecule will be then charged positively four times at neutral pH. (see document attached).

Therefore, given the low LogKow value for IPDA which was estimated to be 1.75 but known to be experimentally of 0.99 and the above mentioned data for IPDA-BADGE-IPDA, as well as the high molecular weight of the other constituents (>1000) which make the constituent not bioavailable, the components are considered to be not Bioaccumulative.

In accordance with column 2 of REACh (Regulation (EC) No 1907/2006) Annex IX, the simulation testing on ultimate degradation in surface water, soil simulation testing, and sediment simulation testing (required in section,, and do not need to be conducted based on the findings of the Chemical Safety Assessment; the substance does not fulfil classification criteria according to the applicable regulations and does not fulfil the criteria for vPvB or PBT.