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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

LC50 (96 h): 35.4 mg/L based on mortality of D. rerio (OECD 203).

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
35.4 mg/L

Additional information

One experimental study was conducted according to OECD 203 and GLP under static conditions. Prior to the definitive test the threshold approach was followed by conducting a limit test with a concentration of 100 mg/L. Since all fish died after 2 h of exposure an additional range-finding test followed by the definitive test with concentrations of 6.25, 12.5, 25.0, 50.0, 100 mg/L were conducted. The test concentrations were analysed by HPLC-DAD at the beginning and the end of exposure. Since they remained within 80-120% of nominal the effect concentrations were based on the nominal values. After 96 h 100% mortality was observed at 50 and 100 mg/L whereas 0% mortality was recorded in the remaining concentrations. The LC50 (96 h) was calculated at 35.4 mg/L (nominal).