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EC number: 944-528-8 | CAS number: -
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2021-07-07 to 2021-07-27
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7950 (Vapor Pressure)
- Version / remarks:
- 1996
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Version / remarks:
- 2006
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- effusion method: Knudsen cell
- Temp.:
- 20 °C
- Vapour pressure:
- 0.6 Pa
- Key result
- Temp.:
- 25 °C
- Vapour pressure:
- 0.92 Pa
- Temp.:
- 50 °C
- Vapour pressure:
- 6.6 Pa
- Conclusions:
- Vapour pressure values of 0.6 Pa (at 20 °C), 0.92 Pa (at 25 °C) and 6.6 Pa (at 50 °C) were determined
for the test substance composition B according to E.U. Method A.4. - Executive summary:
According to OECD Guideline 104 (2006) and Regulation (EC) No 440/2008 Method A.4, the vapour pressure of the substance was calculated by interpolation and extrapolation of the measured vapour pressure curve for the following temperatures:
20 °C: 0.6 Pa
25 °C: 0.92 Pa
50 °C: 6.6 Pa- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 28-Oct-2014
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7950 (Vapor Pressure)
- GLP compliance:
- no
- Type of method:
- dynamic method
- Remarks:
- Vapour-liquid equilibrium
- Key result
- Temp.:
- 20 °C
- Vapour pressure:
- 0.06 hPa
- Key result
- Temp.:
- 25 °C
- Vapour pressure:
- 0.08 hPa
- Key result
- Temp.:
- 50 °C
- Vapour pressure:
- 0.4 hPa
- Conclusions:
- Vapour pressure values of 0.06 hPa (at 20 °C), 0.08 hPa (at 25 °C) and 0.4 hPa (at 50 °C) were determined for the test substance according to E.U. Method A.4.
Referenceopen allclose all
Effusion method: Knudsen cell
No. | Temperature / °C | Vapour pressure / Pa |
1 | 34.5 | 2.04 |
2 | 39.5 | 2.99 |
3 | 49.4 | 6.05 |
4 | 54.5 | 9.63 |
5 | 59.5 | 12.3 |
6 | 64.4 | 18.9 |
7 | 69.5 | 24.4 |
The table shows the logarithm of the vapour pressure log10p as a function of the inverse temperature 1/T. The measured vapour pressure is slightly outside the measuring range (10^-3 to 1 Pa) of the Knudsen cell. Nevertheless, as the vapour pressure value above 1 Pa could be detected properly by the Knudsen cell, this value can be used for the evaluation.
Results
Dynamic method: Vapour-liquid equilibrium (VLE)
The vapour pressure was measured in the temperature range of 134.1 to 218.1 °C. The measured vapour pressure values together with the measured temperatures are listed in the table.
Results of the dynamic method
No. |
Temperature / °C |
Vapour pressure / hPa |
Remark |
1 |
134.1 |
20 |
Measured up |
2 |
157.3 |
40 |
Measured up |
3 |
179.7 |
80 |
Measured up |
4 |
202.1 |
160 |
Measured up |
5 |
218.1 |
250 |
Measured up |
6 |
209.8 |
200 |
Measured down |
7 |
185.6 |
100 |
Measured down |
8 |
164.1 |
50 |
Measured down |
9 |
140.5 |
25 |
Measured down |
From the measured data points of the vapour pressure curve, the constants A, B and C of the Antoine equation were calculated:
Antoine equation:
Log10 ρ = A + B / C + θ
A = 9.7217
B = -2623.77
C = 273.15
Final results
The vapour pressure of the test item was calculated by extrapolation of the measured vapour pressure curve for the temperatures 20, 25 and 50 °C, according to Regulation EC 440/2008 Method A.4. Vapour Pressure.
Calculated vapour pressure values for 20, 25 and 50 °C
Temperature / °C |
Vapour pressure / hPa |
20 |
0.06 |
25 |
0.08 |
50 |
0.40 |
Description of key information
Vapour pressure Composition A: 0.08 hPa at 25 °C (EU Method A.4, dynamic method: vapour-liquid equilibrium)
Vapour pressure Composition B: 0.92 Pa at 25 °C (EU Method A.4, effusion methud: Knudsen cell)
Key value for chemical safety assessment
- Vapour pressure:
- 0.08 hPa
- at the temperature of:
- 25 °C
Additional information
Vapour pressure values of 0.06 hPa (at 20 °C), 0.08 hPa (at 25 °C) and 0.4 hPa (at 50 °C) were determined for the test substance composition A according to E.U. Method A.4.
Vapour pressure values of 0.6 Pa (at 20 °C), 0.92 Pa (at 25 °C) and 6.6 Pa (at 50 °C) were determined for the test substance composition B according to E.U. Method A.4.
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