Registration Dossier
Registration Dossier
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EC number: 941-154-7 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
The short-term toxicity of Benzenesulfonic acid, 4 -C15 -16 -sec-alkyl derivs. was assessed in the three main trophic levels of fresh water organisms (fish, invertebrates and algae). The derived fish 96h-LC50 was 0.17 mg/L (95% confidence interval between 0.13 and 0.24 mg/L) and was already reached after 72 hours of exposure. For Daphnia, a 48h-EC50 of 0.26 mg/l (95% confidence interval between 0.24 and 0.28 mg/l) was obtained. And in the respective study with a fresh water algae, Benzenesulfonic acid, 4-C15-16-sec-alkyl derivs. inhibited growth rate at average exposure concentrations of 9.7 mg/L and higher, resulting in an NOErC (72h) of 3.4 mg/L.. The ErC50 (72h) for growth rate reduction was beyond the range tested and hence > 99 mg/L. The estimated ErC10 (72h) was 5.2 mg/L (95% confidence interval between 2.2 and 9.1 mg/l).
Algae was found to be the least sensitive fresh water organisms out of the three investigated species. Similar findings were presented in the data of the High production Volume (HPV) Chemical Challenge Program: Final revised test plan and assessment with robust study summaries for Linear and Branched Alkylbenzene Sulfonic Acids and Derivatives, Part I: Test Plan and Assessment for LAS/ABS category submitted in April 2008 by The Soap and Detergent Association SDA Linear Alkylbenzene Sulfonate LAS/ Alkyl Benzene Sulfonate ABS Consortium.
The long-term toxicity of Benzenesulfonic acid, 4 -C15 -16 -sec-alkyl derivs. was assessed by using a reliable QSAR model (Ecological Structure-Activity Relationship (ECOSAR) Anionic Surfactant Model (version 1.1) to predict the chronic aquatic toxicity to fish and daphnids. The 28 day No Effect Concentration for fish and the predicted 21 day No Effect Concentration for daphnids were both predicted to be 0.024 mg/L.
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