Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
skin sensitisation, other
Remarks:
test on human volunteers
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2007

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
other: Appraisal of the Safety of Chemicals in Food, Drugs and Cosmetics
Deviations:
yes
Remarks:
100 panelists were tested, not the 200 cited in the reference, and nine inductive patchings were employed, not the ten cited in the reference under occlusive patch conditions.
GLP compliance:
not specified
Type of study:
patch test

Test material

Constituent 1
Chemical structure
Reference substance name:
4-hexylresorcinol
EC Number:
205-257-4
EC Name:
4-hexylresorcinol
Cas Number:
136-77-6
Molecular formula:
C12H18O2
IUPAC Name:
4-hexylresorcinol

Results and discussion

In vivo (LLNA)

Results
Remarks on result:
other: it was not an in vivo test on animals, but on hunman volunteer

Any other information on results incl. tables

No adverse reactions of any kind were noted during the course of this study.

Applicant's summary and conclusion

Conclusions:
The test material when tested under occlusive conditions at 5% dilution in corn oil as described herein, may be considered as a NON-PRIMARY IRRITANT and a NON-PRIMARY SENSITIZER to the skin according to the reference.