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Diss Factsheets
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EC number: 202-433-2 | CAS number: 95-57-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
PBT assessment
Administrative data
PBT assessment: overall result
- Name:
- 2-chlorophenol
- Type of composition:
- boundary composition of the substance
- State / form:
- liquid
- Reference substance:
- 2-chlorophenol
- Name:
- 2-chlorophenol
- Type of composition:
- legal entity composition of the substance
- State / form:
- liquid
- Reference substance:
- 2-chlorophenol
- PBT status:
- the substance is not PBT / vPvB
- Justification:
Persistence Assessment:
A substance is not considered to be persistent if it can be demonstrated that it has potential to degrade (via photolysis, hydrolysis and/or biodegradation). 2-chlorophenol was found to be not readily biodegradable by microorganisms, based on a biodegradation study (according to OECD 301C).
Therefore, based on the result of screening, the P criterion cannot be excluded for 2-chlorophenol .
Bioaccumulation Assessment:
Since the log Kow value of 2-chlorophenol (2.1) is below 4.5 the substance is not expected to be bioaccumulative, based on the screening criteria for bioaccumulation, stipulated in the ECHA’s Guidance on information requirements and chemical safety assessment.
Therefore, 2-chlorophenol does not meet the screening criteria for Bioaccumulation.
Toxicity Assessment:
Environmental Toxicity:
According to Annex XIII of REACH Regulation (EC) No 1907/2006, a substance is considered to be toxic in terms of PBT criteria if long-term NOEC values for aquatic organisms are lower than 0.01 mg/L. The lowest NOEC 0.3 mg/L was obtained in a long-term study with D. magna performed with 2-chlorophenol. Thus, 2-chlorophenol is not considered a toxic substance regarding ecotoxicological endpoints.
Human Health Hazards Assessment:
2-chlorophenol is not classified as carcinogenic, mutagenic or toxic for reproduction, nor is there any evidence of chronic toxicity according to Regulation (EC) No 1272/2008. Thus, 2-chlorophenol is not considered a toxic substance regarding ecotoxicological endpoints.
2-chlorophenol is not considered to be toxic, based on the available data on ecotoxicological and toxicological endpoints, and therefore the substance does not meet the screening criteria for Toxicity.
Summary and overall conclusions on PBT or vPvB Properties:
According to Annex XIII of the REACH Regulation (EC) No 1907/2006, a PBT substance has to fulfil all three of the criteria for persistence, bioaccumulation and toxicity, as listed in part 1 of Annex XIII, and a vPvB substance has to fulfil all criteria for persistence and bioaccumulation, as listed in part 2 of Annex XIII.
Therefore, on the basis of the relevant data provided and discussed, 2-chlorophenol is not identified as PBT or as a vPvB substance (not b, not T, p = inconclusive).
Referenceopen allclose all
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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