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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
data is from experimental reports
Reference:
Composition 1
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Principles of method if other than guideline:
The water solubility determination of test item 3,5-diaminobenzoic acid (CAS No. 535-87-5) was done as per the OECD guideline 105 and by spectrophotometric analytical method as per OECD 101.
GLP compliance:
not specified
Type of method:
flask method
Test material information:
Composition 1
Specific details on test material used for the study:
- Name of test material (as cited in study report): 3,5-Diaminobenzoic acid
- Molecular formula: C7H8N2O2
- Molecular weight: 152.1522 g/mol
- Substance type: Organic
- Physical state: Solid
Key result
Water solubility:
7 839.6 mg/L
Conc. based on:
test mat.
Temp.:
29 °C
Remarks on result:
other: No additional details mentioned

Sample Stirring time (hours)

Concentration obtained on the basis of standard curve (mg/l)

Dilution factor

Solubility value obtained (mg/l)

24

-

-

-

48

3.8214

2000

7642.8

72

4.0182

2000

8036.4

Considering the water solubility for 48 hrs and 72 hrs the mean water solubility was calculated as follows:

Mean water solubility value for 48 hour run sample + 72 hour run sample

=(7642.8+8036.4)/2

=7839.6 mg/L

Conclusions:
The water solubility determination of test item 3,5-diaminobenzoic acid;CAS No.535-87-5 was done by spectrophotometric method. The water solubility was determined to be 7839.6 mg/L at 29°C.
Executive summary:

The water solubility determination of test item 3,5-diaminobenzoic acid (CAS No. 535-87-5) was done as per the OECD guideline 105 and by spectrophotometric analytical method as per OECD 101. The solubility of 3,5-diaminobenzoic acid (CAS: 535-87-5 ) in water was determined to be 7839.6 mg/L at 29°C.

Description of key information

The water solubility determination of test item 3,5-diaminobenzoic acid (CAS No. 535-87-5) was done as per the OECD guideline 105 and by spectrophotometric analytical method as per OECD 101. The solubility of 3,5-diaminobenzoic acid (CAS: 535-87-5 ) in water was determined to be 7839.6 mg/L at 29°C.

Key value for chemical safety assessment

Water solubility:
7 839.6 mg/L
at the temperature of:
29 °C

Additional information

The water solubility determination of test item 3,5-diaminobenzoic acid (CAS No. 535-87-5) was done as per the OECD guideline 105 and by spectrophotometric analytical method as per OECD 101. The solubility of 3,5-diaminobenzoic acid (CAS: 535-87-5 ) in water was determined to be 7839.6 mg/L at 29°C.

Based on this value, 3,5 -Diaminobenzoic acid can be considered to be soluble in water.