Registration Dossier

Toxicological information

Skin sensitisation

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Administrative data

Endpoint:
skin sensitisation, other
Remarks:
in vivo
Type of information:
other: Hand book data
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Secondary literature source

Data source

Reference
Reference Type:
review article or handbook
Title:
Cosmetic and Drug Preservation: Principle and Practise
Author:
Kabara JJ
Year:
1984
Bibliographic source:
Cosmetic Science and Technology Series. Volume 1.

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
Not reported
GLP compliance:
not specified
Type of study:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): Phenethyl alcohol
- Molecular formula : C8H10O
- Molecular weight :112.16
- Substance type: Colorless liquid
- Physical state: liquid
- Other: Solubility: 2 ml dissolves in 100ml water after thorough shaking; miscible with alcohol ( 1part in 1 part 50% alcohol).
Density: 1.0222- 1.0230. Odor: Floral. Stability: Instable with oxidants.

In vivo test system

Test animals

Species:
guinea pig
Strain:
not specified
Sex:
not specified
Details on test animals and environmental conditions:
No data

Results and discussion

Applicant's summary and conclusion

Interpretation of results:
not sensitising
Remarks:
Migrated information
Conclusions:
No sensitisation in concentration of 1-2%.