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EC number: 215-223-0 | CAS number: 1314-15-4; 52785-06-5
In an acute oral toxicity study, an LD50 of greater than 3.4 g/kg bw was reported in male rats gavaged with platinum dioxide, and observed for up to 14 days (Holbrook et al., 1975). No relevant acute dermal or inhalation toxicity data were identified, or are required at this tonnage.
No relevant human acute toxicity data were identified.
In an acute oral toxicity study, groups of male Sprague-Dawley rats were administered platinum dioxide by stomach tube and observed for 14 days. Using the prescribed statistical method, the acute oral median lethal dose (LD50) was found to exceed 3.4 g/kg bw. Based on the results of this study, platinum dioxide should not be classified for acute oral toxicity according to EU CLP criteria (EC 1272/2008).
No acute dermal or inhalation toxicity data were identified, or are required at this tonnage (1-10 tpa).
Based on the results of the available acute oral rat study, platinum dioxide does not require classification for acute oral toxicity according to EU CLP criteria (EC 1272/2008).
No clear evidence of specific target organ toxicity was noted. As such, classification for STOT-SE is not considered appropriate.
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