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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
in vivo mammalian somatic cell study: cytogenicity / erythrocyte micronucleus
Remarks:
Type of genotoxicity: other: genetic toxicity in vivo
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Referenceopen allclose all

Title:
No information
Author:
Anonymous
Year:
2010
Bibliographic source:
OECD Toolbox v2.0, November 2010
Title:
No information
Author:
De Boeck et al.
Bibliographic source:
Environ. Mol.
Title:
No information
Author:
Benigni, R.
Year:
2009
Bibliographic source:
CCRIS & NTP, 2009

Materials and methods

Test guideline
Guideline:
OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)
GLP compliance:
no
Type of assay:
other: genetic toxicity in vivo

Test material

Constituent 1
Chemical structure
Reference substance name:
Benzoin
EC Number:
204-331-3
EC Name:
Benzoin
Cas Number:
119-53-9
Molecular formula:
C14H12O2
IUPAC Name:
2-hydroxy-1,2-diphenylethanone

Test animals

Species:
mouse

Results and discussion

Test results
Sex:
not specified
Genotoxicity:
negative

Applicant's summary and conclusion