Registration Dossier
Registration Dossier
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EC number: 200-929-3 | CAS number: 76-05-1
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation: in vivo (LLNA)
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Study period:
- 2007
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remarks'
- Remarks:
- The study as inserted into the disseminated ECHA dossier is a GLP and an OECD guideline study with a structurally similar compound, ethyl trifluoroacetate. This substance is appropriate for read-across as the ethyl group was not known to induce sensitisation.
Data source
Reference
- Reference Type:
- other: ECHA disseminated dossier
- Title:
- No information
- Report date:
- 2014
Materials and methods
Test material
- Reference substance name:
- Ethyl trifluoroacetate
- EC Number:
- 206-851-6
- EC Name:
- Ethyl trifluoroacetate
- Cas Number:
- 383-63-1
- Molecular formula:
- C4H5F3O2
- IUPAC Name:
- ethyl trifluoroacetate
Constituent 1
Results and discussion
In vivo (LLNA)
Results
- Parameter:
- SI
- Value:
- < 1
Applicant's summary and conclusion
- Interpretation of results:
- not sensitising
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