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Diss Factsheets
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EC number: 243-411-2 | CAS number: 19894-99-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_toxicological-information.png)
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- other information
- Study period:
- No data
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Only a very brief report in a secondary source is available on the unspecified isomer. Primary Russian publication (Volkova et al. 1998) could not be obtained
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- [Unknown]
- Author:
- Volkova NV et al.
- Year:
- 1 998
- Bibliographic source:
- Vrednie chemichescie veshestva. Prirodnie organicheskie soedinenia (Hazardous substances. Nature products), 285
- Reference Type:
- secondary source
- Title:
- Unnamed
- Year:
- 2 003
Materials and methods
- Principles of method if other than guideline:
- No data on methodology given in secondary source
- GLP compliance:
- not specified
- Test type:
- other: no data
Test material
- Reference substance name:
- alpha pinene epoxide (unspecified isomer)
- IUPAC Name:
- alpha pinene epoxide (unspecified isomer)
- Reference substance name:
- 2,7,7-trimethyl-3-oxatricyclo[4.1.1.02,4]octane
- EC Number:
- 216-869-6
- EC Name:
- 2,7,7-trimethyl-3-oxatricyclo[4.1.1.02,4]octane
- Cas Number:
- 1686-14-2
- Molecular formula:
- C10H16O
- IUPAC Name:
- 2,7,7-trimethyl-3-oxatricyclo[4.1.1.0~2,4~]octane
- Test material form:
- not specified
- Details on test material:
- - Name of test material (as cited in study report): pinane, 2,3-epoxy-- Molecular formula (if other than submission substance): C10-H16-O- Molecular weight (if other than submission substance): 152.235- Smiles notation (if other than submission substance): C1([C@@H]2[C@@]3(O[C@@H]3C[C@@H]1C2)C)(C)C- InChl (if other than submission substance): 1S/C10H16O/c1-9(2)6-4-7(9)10(3)8(5-6)11-10/h6-8H,4-5H2,1-3H3 - Structural formula attached as image file (if other than submission substance): see Fig. 1- Substance type: no data in citing source- Physical state: no data in citing source- Analytical purity: no data in citing source- Impurities (identity and concentrations): no data in citing source- Composition of test material, percentage of components: no data in citing source- Isomers composition: no data in citing source- Purity test date: no data in citing source- Lot/batch No.: no data in citing source- Expiration date of the lot/batch: no data in citing source- Stability under test conditions: no data in citing source- Storage condition of test material: no data in citing source
Constituent 1
Constituent 2
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- not specified
- Doses:
- No data in citing source
- No. of animals per sex per dose:
- No data in citing source
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- ca. 2.4 mL/kg bw
- Based on:
- not specified
- Remarks on result:
- other: No exposure duration or confidence intervals given.
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated informationCriteria used for interpretation of results: EU
- Conclusions:
- A secondary source (RTECS) provides limited details of an acute oral [presumably gavage] toxicity study conducted on rats given pinene alpha epoxide (unspecified isomer). The reported oral LD50 was 2.4 ml/kg bw [about 2.4 g/kg bw].
- Executive summary:
A secondary source (RTECS) provides limited details of an acute oral toxicity study conducted on rats given pinene alpha epoxide (unspecified isomer) [presumably by gavage]. [The original Russian publication could not be obtained.] The reported oral LD50 was 2.4 ml/kg bw [about 2.4 g/kg bw].
According to the EU CLP and DSD regulations, this would not require classification for acute oral toxicity.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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