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EC number: 247-979-2 | CAS number: 26761-45-5
The dermal penetration and metabolism of radio-labeled 2,3 -epoxypropyl neodecanoate isomer was assessed in vitro using diffison cell technology with skin samples from rats, mice and humans. The data demonstrated that the 2,3-epoxypropyl neodecanoate isomer was metabolized in vitro in skin samples from rat, mouse and humans to the corresponding diol and ester hydrolysis product. Rat skin was most permeable to the test substance isomer. Human skin samples were approximately an-order-of-magnitude less permeable to the 2,3 -epoxypropyl neodecanoate isomer than rodent skin.
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