Registration Dossier

Administrative data

Endpoint:
pH
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2017-01-20 – 2017-01-20
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
comparable to guideline study
Justification for type of information:
Experimental test result performed using standard test guidelines

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report Date:
2017

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 122 (Determination of pH, Acidity and Alkalinity)
Principles of method if other than guideline:
A pH meter is essentially a voltmeter with high input impedance which measures the voltage of an electrode sensitive to the hydrogen ion concentration, relative to another electrode which exhibits a constant voltage
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
liquid
Details on test material:
- Name of test material: 2-isopropyl-5-methylcyclohexanone
- Molecular formula: C10 H18 O
- Molecular weight: 154.2512g/mol
- Smiles notation: C1([C@@H](CC[C@@H](C1)C)C(C)C)=O
- InChl: 1S/C10H18O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-9H,4-6H2,1-3H3
- Substance type: Organic
- Physical state: liquid
Specific details on test material used for the study:
- Name of test material: (±)-menthone
- Molecular formula: C10 H18 O
- Molecular weight: 154.2512g/mol
- Smiles notation: C1([C@@H](CC[C@@H](C1)C)C(C)C)=O
- InChl: 1S/C10H18O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-9H,4-6H2,1-3H3
- Substance type: Organic
- Physical state: liquid

Results and discussion

pH value
Key result
pH value:
5.82
Temp.:
26 °C
Concentration:
1 other: %w/v

Applicant's summary and conclusion

Conclusions:
pH of 1% w/v aqueous solution of the test substance (±)-menthone (CAS No.1074-95-9) is 5.82 at 26 °C.
Executive summary:

pH of 1% w/v aqueous solution of the test substance (±)-menthone (CAS No.1074-95-9) is determined to be 5.82 at 26 °C. Thus, 1% solution can be considered to be acidic in nature.