Registration Dossier
Registration Dossier
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EC number: 217-195-5 | CAS number: 1771-18-2
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2012
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 012
- Report date:
- 2012
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Methyl phenothiazin-2-yl ether
- EC Number:
- 217-195-5
- EC Name:
- Methyl phenothiazin-2-yl ether
- Cas Number:
- 1771-18-2
- Molecular formula:
- C13H11NOS
- IUPAC Name:
- 2-methoxy-10H-phenothiazine
- Test material form:
- solid: particulate/powder
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- New Zealand White
Test system
- Type of coverage:
- semiocclusive
- Preparation of test site:
- clipped
- Vehicle:
- water
- Duration of treatment / exposure:
- 4 hours
- Observation period:
- 1 hour and then 24, 48, 72 hours
- Number of animals:
- 3
Results and discussion
In vivo
Resultsopen allclose all
- Irritation parameter:
- erythema score
- Basis:
- other: 3 animals
- Time point:
- other: 1 hour, 24 hours, 48 hours and 72 hours
- Score:
- 0
- Irritation parameter:
- edema score
- Basis:
- other: 3 animals
- Time point:
- other: 1 hour, 24 hours, 48 hours and 72 hours
- Score:
- 0
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- The test item must not be classified.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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