Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 224-597-4 | CAS number: 4424-06-0
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
Persistence Assessment
In a Manometric Respirometry Test according to OECD 301 F no biodegradation was observed over a period of 28 days while a functional control (benoic acid, sodium salt) demonstrated the activity of the system.
Therefore, C.I. Pigment Orange 43 is regarded as poorly biodegradable (presumably due to a very restricted bioavailability caused by very low water solubility of 7.2 µg/L). This is in agreement with the desired technological function as pigment. The P- criterion is accepted.
Bioaccumulation Assessment
Due to the low log pow of 0.26, the substance has a low potential for bioaccumulation. The log pow of the substance is very much lower than the threshold value of the screening criterion for B (log pow > 4.5). The B-criterion is not fulfilled.
Toxicity Assessment
The substance is non toxic to mammalian and aquatic organisms. The substance is neither classified for environmental toxicity nor as germ cell mutagen (1A, 1B), carcinogen (1A, 1B), reproductive toxicant (1A, 1B, 2) or specific target organ toxicant after repeated exposure (Cat 1 or 2). It can be concluded that the substance has no toxic properties.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
