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EC number: 253-781-7 | CAS number: 38103-06-9
Score/Effects at 1 Hour
Score/Effects at 24 Hours
Score/Effects at 48 Hours
Score/Effects at 72 Hours
Score/Effects at 7 Days
Other Effects: Rabbit 33780 found dead on Day 6 from unknown causes (probably not dose-related).
The eye irritation potential of the test material was investigated in accordance with the US EPA TSCA Health Effects Test Guidelines under GLP conditions (Bushy Run Research Center, 1988).
Six New Zealand White rabbits were dosed with 0.1 mL (equivalent to 60 mg) of test material per eye. Eye irritation scores were recorded at 1, 24, 48 and 72 hours and at 7 days post-dose.
Treatment resulted in no corneal injury in any of the 6 rabbit eyes. At the 1 hour observation two rabbits displayed iritis in the treated eye and all six rabbits displayed minor conjunctival irritation, with minor to moderate discharge. All six treated eyes were healed after 24 hours.
Under the conditions of this study, the test material is considered to be a non-irritant.
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