Registration Dossier
Registration Dossier
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EC number: 701-059-1 | CAS number: 345217-03-0
Flammability
Administrative data
- Endpoint:
- flammable solids
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 13 March 2012- 11 July 2012
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: The study has been performed according to the EC an UN guidelines and according to the Principles of GLP.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 012
- Report date:
- 2012
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.10 (Flammability (Solids))
- Version / remarks:
- (2008)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: UN no. ST/SG/AC.10/11/Rev.5: Part III: Classification Procedures, Test Methods and Criteria Relating to Class 2, Class 3, Class 4, Division 5.1, Class 8 and Class 9, Test N.1: “Test Method for Readily Combustible Solids” (2009)
- Deviations:
- no
- GLP compliance:
- yes
Test material
- Reference substance name:
- 2,5-anhydro-4-{[4-(4-{4-[({1-[(2S,3S)- 2-(benzyloxy)pentan-3-yl]hydrazino}carbonyl)amino]phenyl}piperazin1-yl)phenoxy]methyl}-1,3,4-trideoxy-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-
- EC Number:
- 701-059-1
- Cas Number:
- 345217-03-0
- Molecular formula:
- C43H50F2N8O4
- IUPAC Name:
- 2,5-anhydro-4-{[4-(4-{4-[({1-[(2S,3S)- 2-(benzyloxy)pentan-3-yl]hydrazino}carbonyl)amino]phenyl}piperazin1-yl)phenoxy]methyl}-1,3,4-trideoxy-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
- Details on test material:
- - Name of test material (as cited in study report): PAZ-D
- Physical state: white powder
- Hygroscopic
Constituent 1
Results and discussion
Any other information on results incl. tables
In contact with the flame of the gas burner the test material melted and turned into a light brown residue. After removal of the ignition source, no propagation of combustion was observed.
Applicant's summary and conclusion
- Interpretation of results:
- non flammable
- Remarks:
- Migrated information
- Conclusions:
- PAZ-D is not highly flammable by ignition. The test was performed in accordance with EC A.10 and UN test N.1 and according to the principles of GLP.
According to CLP Regulation (EC) No. 1272/2008 including its amendments, the substance does not have to be classified for flammability.
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