Registration Dossier
Registration Dossier
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EC number: 247-953-0 | CAS number: 26747-90-0
Endpoint summary
Administrative data
Description of key information
Short-term toxicity to fish:A study was performed to assess the acute toxicity to fish under static conditions following OECD 201. No toxic effects against fish were observed under exposure conditions (96 h-LL50 > 100 mg/L). The results are expressed in terms of Lethal Loading (LL).
Short-term toxicity to invertebrates:The acute toxicity to daphnia magna was investigated in a static GLP study following OECD 202. The study reported of no effects after 48 hours of exposure at a limit effective loading of 100 mg/L (EL 50 >100 mg/L). The results are expressed in terms of Effective Loadings (EL).
Toxicity to aquatic algae:The toxicity was tested in a GLP study following OECD 201 and the exponentially growing algal cells were exposed for a period of 72 hours to a range of test concentrations (4.3, 9.4, 21, 45 and 100 mg/L). The study reported of no effects after 72 hours of exposure (ErL50 > 100 mg/L, NOELr >= 100 mg/L, LOELr > 100 mg/L). The results are expressed in terms of Effective Loading (EL).
Toxicity to micro-organisms:The substancewas exposed to activated sludge of domestic sewage treatment plant in a GLP study following OECD 209. The study reported of no effects after 3 hours of exposure at the limit test concentration (EC50 > 100 mg/L, NOEC >= 100 mg/L). Test concentrations are given as nominal concentrations and have not been confirmed by analytical methods.
Additional information
Isocyanates quickly react with water and form different poly urea compounds. Water Accommodated Fractions (WAFs) were used to test effects at different effective loadings during toxicity studies on algae, invertebrates and fish. The content of the water soluble fractions of the test item during the exposure period was verified by DOC determination.
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