Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 944-260-1 | CAS number: -
Endpoint summary
Administrative data
Description of key information
ACD/Percepta model for acute oral toxicity on mouse and rat provides LD50predictions for mice and rat by oral administration route,based on the GALAS methodology. Reliability of predictions is estimated in terms of reliability index (RI),which ranges from0 to 1 and takes into account the similarity of the target with the training set compounds and the consistency of experimental values for similar compounds.
For 2-Benzyl-4-(dimethylamino)butanoic acid,ACD/Percepta provided anLD50prediction in mouse equal to 2300 mg/kg and an LD50prediction in rat equal to 2500 mg/kg. Both prediction wer assessed as moderate reliable being the reliability index equal respectiely to 0.56 and 0.68.
Key value for chemical safety assessment
Additional information
The prediction was provided on the substance2-Benzyl-4-(dimethylamino)butanoic acid (CAS 1613 -23 -6), the acid form of the substance in the object of the registration.
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
