Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 432-070-7 | CAS number: -
Endpoint summary
Administrative data
Link to relevant study record(s)
- Endpoint:
- basic toxicokinetics
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1976 – 2010
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Objective of study:
- other: corrosive/ irritation effects... (see attached file)
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- Occupational Medical Assessment
- GLP compliance:
- no
- Species:
- human
- Sex:
- male
- Route of administration:
- inhalation: dust
- Vehicle:
- unchanged (no vehicle)
- Details on exposure:
- dermal exposition
- Duration and frequency of treatment / exposure:
- n.a.
- Remarks:
- Doses / Concentrations:
n.a. - No. of animals per sex per dose / concentration:
- n.a.
- Control animals:
- no
- Executive summary:
No indication of specific target-organic toxicity could be determined. This also applies for effects on the respiratory tract and the mucous membranes.
Reference
Description of key information
No indication of corrosive/irritation effects caused by exposure was shown.
Allergic skin sensitization of the employees with long-term exposure can be practically excluded.
Neither reductions of the pulmonary function appeared nor any indication for an inhalative sensitization due to the inhalation of product dust were given. No indication of a development of malignant neoplasia was observed.
No indication of specific target-organic toxicity could be determined. This also applies for effects on the respiratory tract and the mucous membranes.
Key value for chemical safety assessment
- Bioaccumulation potential:
- no bioaccumulation potential
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
