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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1974
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods with acceptable restrictions
Justification for type of information:
None
Qualifier:
according to guideline
Guideline:
other: CIBA Method 11
Version / remarks:
Comparable to internationally accepted guidelines
Deviations:
not applicable
Principles of method if other than guideline:
None
GLP compliance:
no
Specific details on test material used for the study:
None
Analytical monitoring:
no
Details on sampling:
None
Vehicle:
not specified
Details on test solutions:
None
Test organisms (species):
other: rainbow trout
Details on test organisms:
None
Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
48 h
Post exposure observation period:
None
Hardness:
None
Test temperature:
13 °C
pH:
7.9-8.3
Dissolved oxygen:
None
Salinity:
None
Conductivity:
None
Nominal and measured concentrations:
20, 100 and 200 mg/L (nominal)
Details on test conditions:
None
Reference substance (positive control):
not specified
Duration:
48 h
Dose descriptor:
other: TLo
Effect conc.:
20 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Key result
Duration:
48 h
Dose descriptor:
other: TL50
Effect conc.:
57 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
48 h
Dose descriptor:
other: TL100
Effect conc.:
200 mg/L
Nominal / measured:
nominal
Conc. based on:
act. ingr.
Basis for effect:
mortality (fish)
Details on results:
No mortality was observed at 20 mg/L, while 25% (2 out of 8) and 100% (8 out of 8) mortality was observed at 100 and 200 mg/L test concentrations.
Results with reference substance (positive control):
None
Reported statistics and error estimates:
None
Sublethal observations / clinical signs:

None

Validity criteria fulfilled:
no
Conclusions:
The LC50 (TL50) of FAT 20042/A was determined to be 57 mg/L.
Executive summary:

A study investigating short term toxicity of FAT 20042/A to fish was performed according to CIBA method A-11, which is comparable to OECD Guideline 203. Three groups of trouts (each containing 8 fish) was exposed to the test concentrations of 20, 100 and 200 mg/L for 48 hours. No mortality was observed at 20 mg/L, while 25% (2 out of 8) and 100% (8 out of 8) mortality was observed at 100 and 200 mg/L test concentrations. Hence, the LC50 (TL50) of FAT 20042/A was determined to be 57 mg/L.

Description of key information

The LC50 (TL50) of FAT 20042/A  was determined to be 57 mg/L.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
57 mg/L

Additional information

A study investigating short term toxicity of FAT 20042/B to fish was performed according to CIBA method A-11, which is comparable to OECD Guideline 203. Three groups of trouts (each containing 8 fish) was exposed to the test concentrations of 100, 200 and 1000 mg/L for 48 hours. No mortality was observed at 100 and 200 mg/L test concentrations, while 100% (8 out of 8) mortality was observed at 1000 mg/L test concentration. Hence, the LC50 (TL50) of FAT 20042/B was determined to be 450 mg/L.

A study investigating short term toxicity of FAT 20042/A to fish was performed according to CIBA method A-11, which is comparable to OECD Guideline 203. Three groups of trouts (each containing 8 fish) was exposed to the test concentrations of 20, 100 and 200 mg/L for 48 hours. No mortality was observed at 20 mg/L, while 25% (2 out of 8) and 100% (8 out of 8) mortality was observed at 100 and 200 mg/L test concentrations. Hence, the LC50 (TL50) of FAT 20042/A was determined to be 57 mg/L.

Considering the key study data, 48 hour LC50 of FAT 20042/A = 57 mg/l is been considered for hazard assessment to fish.