Registration Dossier
Registration Dossier
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EC number: 269-522-6 | CAS number: 68259-31-4
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Hazard for air
Hazard for terrestrial organisms
Hazard for predators
Additional information
Conclusion on classification
Environmental classification and labelling of a substance is generally based on data from short-term aquatic toxicity results, the ready biodegradability of the substance and an experimentally determined BCF (or if absent the measured octanol/water partition coefficient). Available adequate chronic toxicity data is also relevant for the assessment of long-term aquatic hazards (Regulation 286/2011/EC).
Short-term aquatic toxicity data is available for two trophic levels (daphnia and algae). The reaction mass of 7-isopropyl-5-methylbicyclo[2.2.2]oct-5-ene-2-carbaldehyde and 8-isopropyl-6-methylbicyclo[2.2.2]oct-5-ene-2-carbaldehyde (tradename: Maceal) was determined experimentally to have a 48 -hr Daphnid EC50 of 2.7mg/L. QSAR predicted values are in the same range (1.77 and 1.82 mg/). An algal inhibition study is also available for Maceal which gave a 72-hr ErC50 of >1.449 mg/L.
Since all EC50s are > 1mg/L the substance is not classified for short-term hazards to the aquatic environment according to the CLP Regulation 1272/2008/EC.
Chronic aquatic toxicity data is only available for one trophic level (algae). Therefore, the long-term hazard has been assessed based on both:
a) The chronic aquatic toxicity data for algae (72 hr ErC10 = 0.616 mg/l), which for a non-rapidly degradable substance results in a Chronic 2 classification, and
b) The acute aquatic toxicity data for daphnia (experimental EC50 = 2.7 mg/L) and environmental fate data (not readily biodegradable and log Kow of 4.07 and 4.24, two main constituents), which results in a Chronic 2 classification,
and classifying according to the most stringent outcome.
Thus it is concluded that the substance is classified Aquatic Chronic 2 (H411) according to the CLP Regulation 1272/2008/EC & adaptation 286/2011/EC.
According to the old DSD regulation, Directive 67/548/EEC, the substance would be classified as R51/53 (toxic to aquatic organisms and may cause long-term adverse effects in the aquatic environment).
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