Registration Dossier
Registration Dossier
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EC number: 695-654-2 | CAS number: 1012341-48-8
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 15 September 2008- 18 Septemebr 2008.
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Test performed in accordance with OECD guidelines.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 009
- Report date:
- 2009
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Alga, Growth Inhibition Test)
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.3 (Algal Inhibition test)
- Qualifier:
- according to guideline
- Guideline:
- ISO 8692 (Water Quality - Fresh Water Algal Growth Inhibition Test with Scenedesmus subspicatus and Selenastrum capricornutum)
- Qualifier:
- according to guideline
- Guideline:
- other: Guidance document on aquatic toxicity testing of difficult substances and mixtures, OECD series on testing and assessment number 23, December 14, 2000.
- GLP compliance:
- yes
Test material
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
- Details on test material:
- Substance type: white powder
- Physical state: solid
- Analytical purity: 99.80%
- Expiration date of the lot/batch: 31 Jan 2009
- Storage condition of test material: At room temperature in the dark
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum)
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 72 h
Results and discussion
Effect concentrations
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- <= 28 mg/L
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Remarks:
- at 28 mg/l ( NOEC)
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The EC 50 for both growth rate reduction ( ERC50: 0 -72h) and yield inhibition ( EYC50: 0 -72h) was beyond 28 mg/l.
- Executive summary:
Under the conditions of the study with pseudokirchneriella subcapitata, the test substance did not reduce growth rate of this freshwater algae species at 28mg/l (NOEC). Yield inhibition was statically inhibited by 22% ( NOEC < 28 mg/l).
The EC 50 for both growth rate reduction ( ERC50: 0 -72h) and yield inhibition ( EYC50: 0 -72h) was beyond 28 mg/l.
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