Registration Dossier

Administrative data

Key value for chemical safety assessment

Additional information

A bacterial reverse mutation test was performed by Huntingdon Life Sciences, UK, to assess the potential of the test substance to cause gene mutation. The study was conducted to OECD, EC and US EPA was performed in compliance with GLP. In each of two tests, no evidence of cytotoxicity was observed, and no increase in the number of revertant colonies relative to the controls were seen. It was concluded that the test substance showed no evidence of mutagenic activity in the bacterial system under the test conditions employed.


Short description of key information:
In a bacterial reverse mutation assay, the test substance was not found to display any evidence of mutagenic potential.

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

A bacterial reverse mutation test was performed on the test substance to assess the potential of the test substance to cause gene mutation. No evidence of mutagenic activity was observed in the test. The test substance does not require classification according to EC Directive 67/548/EEC on the basis of this result.