Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Key result
- Water solubility:
- 382 g/L
- Temp.:
- 20 °C
- pH:
- 8.52
- Details on results:
- The individual results for the determination at three consecutive sampling dates (0h-48h) do not differ by more than 15%. Therefore, a saturation of the water phase with the test item can be assumed and the water solubility is calculated as the mean value of the results between 0h and 48h.
- Conclusions:
- The water solubility of the test item in bidistilled water at 20 ± 0.5 ºC is determined to be 382 g/L. The average pH of the saturated solution was pH 8.52.
- Executive summary:
The water solubility of the test item was determined according to OECD guideline 105 and EC method A.6. The water solubility of the test item in bidistilled water at 20 ± 0.5 ºC is determined to be 382 g/L. The average pH of the saturated solution was pH 8.52.
Reference
Description of key information
Key study: OECD guideline 105 and EC method A.6. GLP study.
The water solubility of the test item in bidistilled water at 20 ± 0.5 ºC is determined to be 382 g/L. The average pH of the saturated solution was pH 8.52.
Key value for chemical safety assessment
- Water solubility:
- 382 g/L
- at the temperature of:
- 20 °C
Additional information
Key study: OECD guideline 105 and EC method A.6. GLP study.
The water solubility of the test item in bidistilled water at 20 ± 0.5 ºC is determined to be 382 g/L. The average pH of the saturated solution was pH 8.52.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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