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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
basic toxicokinetics, other
Type of information:
other: Assessment based on physicochemical properties and available toxicological data
Adequacy of study:
key study
Study period:
2017
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
Objective of study:
absorption
distribution
excretion
metabolism
toxicokinetics
Principles of method if other than guideline:
Toxicokinetic assesment based on the available physicochemical and toxicological data as per the ECHA Guidance R.7c
GLP compliance:
no
Conclusions:
REACTIVE YELLOW 095 would be absorbed primarily in gastrointestinal tract, while limited absorption via dermal and inhalation exposure can be expected. Systemic distribution would most likely occur via the serum, while metabolism would be limited and not required to facilitate renal excretion.
Executive summary:

REACTIVE YELLOW 095 would be absorbed primarily in gastrointestinal tract, while limited absorption via dermal and inhalation exposure can be expected. Systemic distribution would most likely occur via the serum, while metabolism would be limited and not required to facilitate renal excretion.

Description of key information

REACTIVE YELLOW 095 would be absorbed primarily in gastrointestinal tract, while limited absorption via dermal and inhalation exposure can be expected. Systemic distribution would most likely occur via the serum, while metabolism would be limited and not required to facilitate renal excretion.

Key value for chemical safety assessment

Bioaccumulation potential:
no bioaccumulation potential
Absorption rate - oral (%):
100
Absorption rate - dermal (%):
4
Absorption rate - inhalation (%):
100

Additional information