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Ecotoxicological information

Short-term toxicity to fish

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Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1984
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
Justification for type of information:
None
Qualifier:
according to guideline
Guideline:
other: CIBA Method A-11
Principles of method if other than guideline:
None
GLP compliance:
no
Specific details on test material used for the study:
None
Analytical monitoring:
yes
Details on sampling:
None
Vehicle:
yes
Details on test solutions:
Water
Test organisms (species):
Danio rerio (previous name: Brachydanio rerio)
Details on test organisms:
None
Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
96 h
Remarks on exposure duration:
None
Post exposure observation period:
None
Hardness:
None
Test temperature:
23 °C
pH:
10
Dissolved oxygen:
None
Salinity:
None
Conductivity:
None
Nominal and measured concentrations:
300 and 1000 mg/l
Details on test conditions:
None
Reference substance (positive control):
not specified
Duration:
96 h
Dose descriptor:
LC0
Effect conc.:
300 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Key result
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
> 1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
LC100
Effect conc.:
> 1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Details on results:
None
Results with reference substance (positive control):
None
Reported statistics and error estimates:
None
Sublethal observations / clinical signs:

None

Validity criteria fulfilled:
not specified
Conclusions:
The LC50 of FAT 40000/E in this fish acute toxicity test was determined to be greater than 1000 mg/L.
Executive summary:

An acute fish toxicity test was performed with Zebra-fish (Brachydanio rerio). Groups of fish were exposed at the test concentrationsof 300 and 1000 mg/L. Based on the findings, the LC0 value was determined to be 300 mg/l. The LC50 and LC100 value was determined to be greater than 1000 mg/l.

Description of key information

The LC50 of FAT 40000 was determined to be greater than 1000 mg/L.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
1 000 mg/L

Additional information

A key study to determine acute toxicity to fish was performed with Zebra-fish (Brachydanio rerio). Groups of fish were exposed at the test concentrations of 300 and 1000 mg/L. Based on the findings, the LC0 values was 300 whereas LC50 and LC100 value was determined to be greater than 1000 mg/l. Several other studies conducted on different batches of this test material and involving different species confirmed this test result indication no species-dependent or production process and batch-dependent effects.

Overall result:

LC50 = >1000 mg/l.