Registration Dossier

Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study without detailed documentation

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2005

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed

Test animals

Species:
rabbit
Strain:
New Zealand White

Test system

Amount / concentration applied:
The test material was given in a single dose of 0.5g/animal with a 4-hour exposure on the intact hairless skin.
Duration of treatment / exposure:
4 h
Observation period:
14 day

Results and discussion

In vivo

Results
Remarks on result:
no indication of irritation
Irritant / corrosive response data:
No irritation symptoms (erythema or edema) or other changes were observed.

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met