Registration Dossier
Registration Dossier
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EC number: 204-258-7 | CAS number: 118-52-5
Endpoint summary
Administrative data
Description of key information
The acute toxicity data available for 1,3-dichloro-5,5-dimethylhydantoin are: LD50 rat oral = 542 mg/kg/bw, LD50 inhalation rat 1h = 20.5 g/m3 and LD50 dermal rabbit > 20000 mg/kg/bw.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 542 mg/kg bw
- Quality of whole database:
- Data reported by Health Council of the Netherlands in the document "Committee on Updating of Occupational Exposure Limits. 1,3-Dichloro-5,5-dimethylhydantoin, 2000/15OSH/046, 31 October 2002"
Acute toxicity: via inhalation route
Endpoint conclusion
- Dose descriptor:
- LC50
- Value:
- 20 500 mg/m³ air
- Quality of whole database:
- Data reported by Health Council of the Netherlands in the document "Committee on Updating of Occupational Exposure Limits. 1,3-Dichloro-5,5-dimethylhydantoin, 2000/15OSH/046, 31 October 2002"
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 20 000 mg/kg bw
- Quality of whole database:
- Data reported by Health Council of the Netherlands in the document "Committee on Updating of Occupational Exposure Limits. 1,3-Dichloro-5,5-dimethylhydantoin, 2000/15OSH/046, 31 October 2002"
Additional information
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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