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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
flammable solids
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Report date:
2014

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.10 (Flammability (Solids))
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Loperamide
EC Number:
258-416-5
EC Name:
Loperamide
Cas Number:
53179-11-6
Molecular formula:
C29H33ClN2O2
IUPAC Name:
4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder
Details on test material:
Test item identification : 4-(4-clorofenil)-4-idrossi-N,N-dimetil-a,a-difenil-1--piperidinbutanamide
Purity : 99.7 % w/w
Expiry date : June 01, 2015

Results and discussion

Any other information on results incl. tables

Two preliminary tests were performed and the same sample behaviour was observed.

The test item, a white powder, did not ignite, but the solid sample melted when the Bunsen

burner flame came close.

Since test item did not propagate combustion, no further testing was required.

Applicant's summary and conclusion

Interpretation of results:
non flammable
Remarks:
Migrated information
Conclusions:
From the obtained experimental data according to the A.10 method in Council Regulation
(EC) No 440/2008 of 30 May 2008, it can be concluded that the 4-(4-chlorophenyl)-4-
hydroxy-N,N-dimethyl-a,a-diphenyl sample is a not highly flammable substance.