Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Not harmful/toxic for aquatic life.

Additional information

Adequate chronic toxicity data are not available for Direct Red 253, therefore the aquatic toxicity assessment and classification are based mainly on the short-term toxicity data available on the substance and on analogue Similar Substance 01.

Direct Red 253 is very water soluble (i.e. < 100 g/l); it has a log Kow lower than 4 (indicating a low potential for bioaccumulation) and is not rapidly degradable.

According to the CLP Regulation (EC 1272/2008), acute aquatic toxicity is normally determined using a fish 96-hour LC50, a crustacean species 48-hour EC50 and/or an algal species 72- or 96-hour EC50. These species cover a range of trophic levels and taxa and are considered as surrogate for all aquatic organisms.

Data are available for fish (orange-red killifish and rainbow trout), Daphnia magna and Scenedesmus subspicatus.

According to the CLP Regulation (EC 12720/2008) criteria for the identification of the classification categories for hazardous to the aquatic environment, all studies about short-term toxicity to fish, invertebrates and algae fixed the short-term effect level higher than 100 mg/l.

The outcomes of the tests performed on the three trophic levels suggest that the substance is not harmful/toxic for aquatic life.

In conclusion, the Direct Red 253 does not meet the criteria to be classified harmful/toxic for aquatic life, according to the CLP Regulation (EC 1272/2008).