Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015
Report date:
2015

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
The test item is not stable in water or under the influence of humidity (see GLP-study no. 15L00071 from Competence Center Analytics, BASF SE, D-67056 Ludwigshafen). Due to that the determination of the log Pow corresponding to the OECD Guideline for the Testing of Chemicals 107 (shake flask method) is not feasible.
GLP compliance:
yes (incl. QA statement)
Type of method:
estimation method (solubility ratio)
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
1,3,5-Benzenetricarboxylic acid, copper(2+) salt (2:3)
Cas Number:
309721-49-1
Molecular formula:
C9 H6 O6 . 3/2 Cu
IUPAC Name:
1,3,5-Benzenetricarboxylic acid, copper(2+) salt (2:3)
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder
Details on test material:
Name of test material (as cited in study report): 1,3,5-Benzenetricarboxylic acid, copper(2+) salt (2:3)
Analytical purity: >= 97%
Lot/batch No.: AP199.6
Expiration date of the lot/batch: Sep 01, 2014
Storage condition of test material: Ambient temperature, nitrogen atmosphere

Results and discussion

Partition coefficient
Remarks on result:
other: The Pow of the test item cannot be determined

Any other information on results incl. tables

The Pow of the test item cannot be determined according to the shake flask method (OECD Guideline for the Testing of

Chemicals 107), because of the knowledge of the instability of the test item in aqueous systems or under the influence of

humidity.

The HPLC method (OECD Guideline for the Testing of Chemicals 117) is also not suitable to determine Pow, because the test

item cannot be chromatographed under the prescribed conditions.

Because of the instability of the test item in water and under the influence of humidity, the Pow cannot even be estimated

from the single solubilities in n-octanol and water.

Applicant's summary and conclusion