Registration Dossier

Administrative data

Endpoint:
fish early-life stage toxicity
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: GLP gudeline study but only limited data available (secondary source)

Data source

Referenceopen allclose all

Reference Type:
study report
Title:
Unnamed
Year:
1991
Report Date:
1991
Reference Type:
secondary source
Title:
European Union Risk Assessment Report, dibutyl phthalate, CAS No: 84-74-2, EINECS No: 201-557-4
Author:
EU
Year:
2004
Bibliographic source:
European Chemicals Bureau

Materials and methods

Principles of method if other than guideline:
Method: EnviroSystems Test Protocol 9102-CMA / Early life stage toxicity test with rainbow trout
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- purity: 99.9 %

Sampling and analysis

Analytical monitoring:
yes

Test solutions

Vehicle:
yes
Details on test solutions:
acetone

Test organisms

Test organisms (species):
Oncorhynchus mykiss (previous name: Salmo gairdneri)

Study design

Test type:
flow-through
Water media type:
freshwater
Limit test:
no
Total exposure duration:
99 d

Test conditions

Hardness:
180 mg/L as CaCo3
Nominal and measured concentrations:
0.14, 0.26, 0.52, 1.0, 2.0 mg/L (nominal)
0.1, 0.19, 0.40, 0.89, 1.7 mg/L (measured)

Results and discussion

Effect concentrationsopen allclose all
Duration:
99 d
Dose descriptor:
LOEC
Effect conc.:
0.19 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
length
Remarks:
and weight
Duration:
99 d
Dose descriptor:
NOEC
Effect conc.:
0.1 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
length
Remarks:
and weight

Applicant's summary and conclusion