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Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
19 May - 18 July, 2014
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: A modern GLP study conducted according the appropriate guidelines.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2014
Report date:
2014

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
Linalyl propionate
EC Number:
205-627-5
EC Name:
Linalyl propionate
Cas Number:
144-39-8
Molecular formula:
C13H22O2
IUPAC Name:
linalyl propionate
impurity 1
Reference substance name:
Unknown impurities
Molecular formula:
not applicable
IUPAC Name:
Unknown impurities
Test material form:
liquid
Details on test material:
- Name of test material (as cited in study report): Linalyl propionate
- Molecular formula: C13H22O2
- Molecular weight: 210.3 g/mol
- Analytical purity: 100.0%
- Lot/batch No.: SC00010215
- Expiration date of the lot/batch: 12 January 2015
- Storage condition of test material: room temperature, in the dark

Results and discussion

Water solubility
Water solubility:
0.009 g/L
Temp.:
20 °C
Remarks on result:
other: The test item significantly degraded/hydrolyzed in water with increased initial saturation/exposure period leading to accumulation of hydrolysis/degradation products and a decrease in the contribution of the parent to the total sample response.
Details on results:
The water solubility of the parent test item has been determined to be 8.72 x 10-3 g/L of solution at 20.0 ± 0.5 °C. However, the test item was identified to degrade/hydrolyze in the presence of water, with an increased initial saturation/exposure period leading to an accumulation of hydrolysis/degradation products and a decrease in the contribution of the parent test item to the total sample response on analysis.
On analysis of the short-term evaluation of water solubility sample prepared during preliminary testing, evidence of hydrolysis/degradation was still evident even after reducing saturation and re-equilibration periods to only one hour each.

Any other information on results incl. tables

No further data

Applicant's summary and conclusion

Conclusions:
The water solubility of Linalyl propionate was 8.72 x 10-3 g/L of solution for the parent test item at 20.0 ± 0.5 °C.
Executive summary:

The water solubility of Linalyl propionate was measured according to OECD Guideline No. 105 (flask method).

The water solubility of Linalyl propionate was 8.72 x 10-3 g/L of solution for the parent test item at 20.0 ± 0.5 °C.

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