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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
28 September 2010 to 25 November 2010
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP compliant, guideline study. Available as an unpublished report. Acceptable without restrictions.
Reference:
Composition 1
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
flask method
Test material information:
Composition 1
Water solubility:
0.922 g/L
Temp.:
20 °C
pH:
>= 3.2 - <= 3.7
Details on results:
The water solubility of the test item has been determined to be at least 0.437g/l of solution at 20.0 ± 0.5 °C monitoring the palladium concentration of the sample solutions; equivalent to a palladium acetate solubility of at least 0.922 g/l of solution at 20.0 ± 0.5 °C. However, the solubilised palladium content of the sample solutions was confirmed to be unstable, with a decreasing concentration being obtained when applying the standard test method with stepwise extension of the initial sample saturation period. the definitive test result reported was obtained from a preliminary test from which the maximum observed solubility was achieved, applying an initial saturation period of 18.5 hrs and a final equilibration period of 4 hours respectively.
Conclusions:
The water solubility of the test item has been determined to be at least 0.437g/l of solution at 20.0 ± 0.5 °C monitoring the palladium concentration of the sample solutions; equivalent to a palladium acetate solubility of at least 0.922 g/l of solution at 20.0 ± 0.5 °C. However, the solubilised palladium content of the sample solutions was confirmed to be unstable, with a decreasing concentration being obtained when applying the standard test method with stepwise extension of the initial sample saturation period. the definitive test result reported was obtained from a preliminary test from which the maximum observed solubility was achieved, applying an initial saturation period of 18.5 hrs and a final equilibration period of 4 hours respectively.
Executive summary:

This is a GLP compliant, guideline study considered suitable for use as the key study for this endpoint.

The water solubility of the test item has been determined to be at least 0.437g/l of solution at 20.0 ± 0.5 °C monitoring the palladium concentration of the sample solutions; equivalent to a palladium acetate solubility of at least 0.922 g/l of solution at 20.0 ± 0.5 °C. However, the solubilised palladium content of the sample solutions was confirmed to be unstable, with a decreasing concentration being obtained when applying the standard test method with stepwise extension of the initial sample saturation period. the definitive test result reported was obtained from a preliminary test from which the maximum observed solubility was achieved, applying an initial saturation period of 18.5 hrs and a final equilibration period of 4 hours respectively.

Description of key information

The water solubility of palladium (II) acetate has been determined to be at least 0.437 g/l of solution at 20.0 ± 0.5 °C monitoring the palladium concentration of the sample solutions; equivalent to a palladium acetate solubility of at least 0.922 g/l of solution at 20.0 ± 0.5 °C.

Key value for chemical safety assessment

Water solubility:
0.922 g/L
at the temperature of:
20 °C

Additional information

O’Connor and Woolley (2011) conducted a GLP compliant study following OECD TG 105 and is considered suitable for use as the key study for this endpoint. The water solubility of the test item has been determined to be at least 0.437g/l of solution at 20.0 ± 0.5 °C monitoring the palladium concentration of the sample solutions; equivalent to a palladium acetate solubility of at least 0.922 g/l of solution at 20.0 ± 0.5 °C. However, the solubilised palladium content of the sample solutions was confirmed to be unstable, with a decreasing concentration being obtained when applying the standard test method with stepwise extension of the initial sample saturation period. The definitive test result reported was obtained from a preliminary test from which the maximum observed solubility was achieved, applying an initial saturation period of 18.5 hrs and a final equilibration period of 4 hours respectively