Registration Dossier
Registration Dossier
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EC number: 229-942-2 | CAS number: 6850-63-1
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Based on a read-across approach from the structurally analogous compound 2-ethylcyclohexylamine (CAS 7003-32-9), the target substance 2,6-dimethylcyclohexylamine (CAS 6850-63-1) is assessed to be readily degradable (according to OECD criteria).
Key value for chemical safety assessment
Additional information
The assessment of the biodegradability of 2,6-dimethylcyclohexylamine (CAS 6850-63-1) is based on read-across data from an OECD 301A (DOC die away test) GLP guideline study with the structural analogue 2 -methylcyclohexylamine (CAS 7003-32-9), using non-adapted activated sludge (predominantly domestic) as inoculum (BASF AG, 1996). After 28 days, biodegradation was 95%; the ten-day window was met.
Supporting experimental data are available for 2,6-dimethylcyclohexylamine (CAS 6850-63-1) from a Zahn-Wellens test (conducted similar to OECD 302B) with industrial, activated sludge as inoculum (adaptation not specified; BASF, 1998). Based on DOC removal, the degradation was determined to be 88% after 24 days, indicating the substance to be inherently biodegradable.
Conclusion:
Based on the available read-across data for the analogous compound 2 -methylcyclohexylamine (CAS 7003-32-9), supported by experimental data from a Zahn-Wellens test with the target substance itself, 2,6-dimethylcyclohexylamine (CAS 6850-63-1) is concluded to be readily degradable (according to OECD criteria).
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