Registration Dossier
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EC number: 259-105-7 | CAS number: 54326-11-3
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Based on read across the acute toxicity of (benzoato-O,O')hydroxy(octadecanoato-O,O')aluminium to the freshwater fish rainbow trout (Oncorhynchus mykiss) is predicted to show no effects at a water accommodated fraction nominal loading rate of 100 mg/L. Therefore, the 96 hour LL50 is determined to be > 100 mg/L (WAF).
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 100 mg/L
Additional information
As no data was available for the short-term toxicity to fish of (benzoato-O,O')hydroxy(octadecanoato-O,O')aluminium the endpoint was read across from aluminum, benzoate C16-18-fatty acids complexes.The acute toxicity of the read-across substance to rainbow trout (Oncorhynchus mykiss) was determined in a proprietary, GLP-compliant, semi-static limit test (Harlan 2013) following OECD guideline 203. As no effects were observed in the Daphnia and algae toxicity tests or the preliminary range finding test for acute toxicity to fish, the definitive toxicity to fish test was conducted as a limit test at a nominal loading rate of 100 mg/L alongside a blank control. Seven fish were exposed to a water accommodated fraction (WAF) of aluminum, benzoate C16-18-fatty acids complexes for 96 hours in standard ecotoxicity media adjusted to a hardness of approximately 150 mg/L CaCO3. Observations of mortalities or abnormalities of behaviour or appearance of the fish was made at 3, 6, 24, 48, 72 and 96 hours and the test solutions analysed for aluminium content and total organic carbon at test initiation and termination. As no toxicity effects were observed, the 96 hour LL50 is determined to be > 100 mg/L (WAF).
Aluminum, benzoate C16-18-fatty acids complexes (CAS No. 94166-87-7, EC No. 303-385-6) is considered suitable for read across to (benzoato-O,O')hydroxy(octadecanoato-O,O')aluminium as it is structurally similar being an approximate 2:1 mixture of (benzoato-O,O')hydroxy(octadecanoato-O,O')aluminium and (benzoato-O,O')hydroxy(hexadecanoato-O,O')aluminium. The only significant difference is the presence of about 30% of the aluminium complex containing the saturated C16-fatty acid, hexadecanoate, in place of the saturated C18-fatty acid, octadecanoate. This small difference in composition is expected to have no adverse influence on the short-term toxicity to fish.
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