Registration Dossier
Registration Dossier
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EC number: 276-911-4 | CAS number: 72829-25-5
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to microorganisms, other
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Study period:
- 1975
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods with acceptable restrictions
- Justification for type of information:
- Refer chapter 13 for the detailed analogue justification.
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- according to guideline
- Guideline:
- other: Inhouse SOP (method B.10) validated by Ciba which is comparable to standard guideline.
- Deviations:
- not specified
- Principles of method if other than guideline:
- Inhouse SOP (method B.10) validated by Ciba which is comparable to standard guideline.
- GLP compliance:
- no
- Analytical monitoring:
- yes
- Vehicle:
- not specified
- Test organisms (species):
- activated sludge
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 3 h
- Remarks on exposure duration:
- None
- Reference substance (positive control):
- not specified
- Key result
- Duration:
- 3 h
- Dose descriptor:
- IC50
- Effect conc.:
- > 300 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth inhibition
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The IC50 for FAT 40034/A was found to be greater than 300 mg/L.
- Executive summary:
The toxicity of FAT 40034/A to activated sludge was determined in a 3-h respiration inhibition test according inhouse SOP (method B.10) validated by Ciba which is comparable to standard guideline. Based on the findings of the study, the IC50 of the test substance FAT 40034/A is greater than 300 mg/L.
Reference
Description of key information
The BST of the test substance Reactive Red 24:1(basis of source substance-FAT 40034/A) is greater than 300 mg/L.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 300 mg/L
Additional information
The toxicity of FAT 40034/A (source substance) to activated sludge was determined in a 3-h respiration inhibition test according In house SOP (method B.10) validated by Ciba which is comparable to standard guideline.
So, based on source substance data, the BST of Reactive Red 24:1 is greater than 300 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
