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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Particle size distribution (Granulometry)

Administrative data

Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Test procedure in accordance with generally accepted scientific standards and described in sufficient detail; however, non-GLP

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2016
Report date:
2016

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Laser diffraction
GLP compliance:
no
Type of method:
Laser scattering/diffraction
Type of distribution:
volumetric distribution

Test material

Constituent 1
Chemical structure
Reference substance name:
Sodium 3-[[(dimethylamino)thioxomethyl]thio]propanesulphonate
EC Number:
242-644-7
EC Name:
Sodium 3-[[(dimethylamino)thioxomethyl]thio]propanesulphonate
Cas Number:
18880-36-9
Molecular formula:
C6H13NO3S3.Na
IUPAC Name:
sodium 3-[(dimethylcarbamothioyl)sulfanyl]propane-1-sulfonate
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder

Results and discussion

Particle sizeopen allclose all
Key result
Percentile:
D10
Mean:
1.55 µm
Remarks on result:
other: standard deviation not available
Key result
Percentile:
other: D25
Mean:
5 µm
Remarks on result:
other: standard deviation not available
Key result
Percentile:
D50
Mean:
31.15 µm
Remarks on result:
other: standard deviation not available
Key result
Percentile:
D90
Mean:
168.49 µm
Remarks on result:
other: standard deviation not available

Any other information on results incl. tables

Concentration: 0.0004 %Vol

Uniformity: 1.7

Span: 5.360

Specific surface area: 1.42 m2/g

Surface weighted mean D [3,2]: 4.220 µm

Vol. weighted mean D [4,3]: 61.233 μm

D(0.10): 1.55 μm

D(0.50): 31.15 μm

D(0.90): 168.49 μm

Applicant's summary and conclusion

Conclusions:
Average size of particles = 61.233 μm
D10 = 1.55 μm
D25 = 5.00 µm
D50 = 31.15 μm
D90 = 168.49 μm
Executive summary:

The particle size distribution of the test substance was investigated by laser diffraction based on Mie Scattering (non-GLP, 2016) and the average size of particles has been determined to be 61.233 µm (D10 = 1.55 µm, D25 = 5.00 µm, D50 = 31.15 µm, D90 = 168.49 µm).

According to the results, the inhalation of particles has to be regarded:

- ~ 75% are <100 µm (inhalable fraction)

- ~ 34% are <10 µm (thoracic fraction)

- ~20% are < 4µm (respirable fraction)