α,2,4-trichlorotoluene

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:

short-term toxicity to aquatic invertebrates

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

comparable to guideline study with acceptable restrictions

Data source

Reference

Reference Type:

publication

Title:

Toxicity of aryl- and benzylhalides to Daphnia magna and classification of their mode of action based on quantitative structure-activity relationship

Author:

Marchini, Silvia; Passerini, Laura; Hoglund Marrilynn D.; Pino Anna; Nendza, Monika

Year:

1999

Bibliographic source:

Environmental Toxicology and Chemistry (1999), 18(12), 2759-2766

Materials and methods

Test organisms

Test organisms (species):

Daphnia magna

Study design

Test type:

static

Total exposure duration:

48 h

Test conditions

Test temperature:

21.5 +/- 1°C

Dissolved oxygen:

> 75%

Results and discussion

Effect concentrations

Key result

Duration:

48 h

Dose descriptor:

EC50

Effect conc.:

0.12 mg/L

Nominal / measured:

meas. (arithm. mean)

Conc. based on:

test mat.

Basis for effect:

mobility

Applicant's summary and conclusion

Validity criteria fulfilled:

yes

Conclusions:

The EC50 (48h) of the test substance is 0.12 mg/L