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Short-term toxicity to aquatic invertebrates

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Description of key information

Butyldiethanolamine_OECD 202: EC50 (48 h) > 100 mg/L

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
100 mg/L

Additional information

A study (Ladwa, 2015) according to OECD Guideline 202 was conducted to determine the acute toxicity of the substance butyldiethanolamine (CAS 102-79-4) towards Daphnia magna in compliance with GLP. Following a preliminary range-finding test and initial experiment, twenty daphnids (4 replicates of 5 animals) were exposed to an aqueous solution of the test item at concentrations of 10, 18, 32, 56 and 100 mg/L for 48 hours at a temperature of approximately 21 °C under static test conditions. The numbers of immobilized daphnia were recorded after 24 and 48 hours.

Analysis of the test preparations at 0 and 48 hours showed measured test concentrations to range from 106 % to 125% of nominal concentration and so the results are based on nominal test concentrations. Exposure of Daphnia magna to the test item gave EC50 values of greater than 100 mg/L. The No Observed Effect Concentration was 100 mg/L. Results with the reference substance potassium dichromate were valid.